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Fine-tuning of NFκB by Glycogen Synthase Kinase 3β directs the fate of glomerular podocytes upon injury

NFκB is regulated by a myriad of signaling cascades including glycogen synthase kinase (GSK) 3β and plays a Janus role in podocyte injury. In vitro, lipopolysaccharide or adriamycin elicited podocyte injury and cytoskeletal disruption, associated with NFκB activation and induced expression of NFκB t...

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Bibliografiske detaljer
Udgivet i:Kidney Int
Main Authors: Bao, Hui, Ge, Yan, Peng, Ai, Gong, Rujun
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449834/
https://ncbi.nlm.nih.gov/pubmed/25629551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2014.428
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