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Glycogen Synthase Kinase 3β Dictates Podocyte Motility and Focal Adhesion Turnover by Modulating Paxillin Activity: Implications for the Protective Effect of Low-Dose Lithium in Podocytopathy
Aberrant focal adhesion turnover is centrally involved in podocyte actin cytoskeleton disorganization and foot process effacement. The structural and dynamic integrity of focal adhesions is orchestrated by multiple cell signaling molecules, including glycogen synthase kinase 3β (GSK3β), a multitaski...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Investigative Pathology
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4188873/ https://ncbi.nlm.nih.gov/pubmed/25239564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.06.027 |
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