Interaction of Paxillin with Poly(A)-Binding Protein 1 and Its Role in Focal Adhesion Turnover and Cell Migration

We have previously identified poly(A)-binding protein 1 (PABP1) as a ligand for paxillin and shown that the paxillin-PABP1 complex undergoes nucleocytoplasmic shuttling. By targeting the paxillin-binding subdomain sequences in PABP1, we have generated mutants of PABP1 that do not bind to cellular pa...

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Bibliografiske detaljer
Main Authors: Woods, Alison J., Kantidakis, Theodoros, Sabe, Hisataka, Critchley, David R., Norman, Jim C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084280/
https://ncbi.nlm.nih.gov/pubmed/15831480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3763-3773.2005
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