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Growth hormone receptor (GHR) gene polymorphism and scoliosis in Prader-Willi syndrome

OBJECTIVE: A growth hormone receptor (GHR) gene polymorphism impacts sensitivity to endogenous and exogenous growth hormone (GH) to moderate growth and development. Increased sensitivity may accelerate spinal growth and contribute to scoliosis, particularly in GH-deficient and treated populations su...

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Bibliografiske detaljer
Udgivet i:Growth Horm IGF Res
Main Authors: Butler, Merlin G., Hossain, Waheeda, Hassan, Maaz, Manzardo, Ann M.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668334/
https://ncbi.nlm.nih.gov/pubmed/29273483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2017.12.001
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