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Growth hormone receptor (GHR) gene polymorphism and scoliosis in Prader-Willi syndrome

OBJECTIVE: A growth hormone receptor (GHR) gene polymorphism impacts sensitivity to endogenous and exogenous growth hormone (GH) to moderate growth and development. Increased sensitivity may accelerate spinal growth and contribute to scoliosis, particularly in GH-deficient and treated populations su...

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Bibliografische gegevens
Gepubliceerd in:Growth Horm IGF Res
Hoofdauteurs: Butler, Merlin G., Hossain, Waheeda, Hassan, Maaz, Manzardo, Ann M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668334/
https://ncbi.nlm.nih.gov/pubmed/29273483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2017.12.001
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