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Growth hormone receptor (GHR) gene polymorphism and scoliosis in Prader-Willi syndrome

OBJECTIVE: A growth hormone receptor (GHR) gene polymorphism impacts sensitivity to endogenous and exogenous growth hormone (GH) to moderate growth and development. Increased sensitivity may accelerate spinal growth and contribute to scoliosis, particularly in GH-deficient and treated populations su...

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Detalles Bibliográficos
Publicado en:Growth Horm IGF Res
Autores principales: Butler, Merlin G., Hossain, Waheeda, Hassan, Maaz, Manzardo, Ann M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668334/
https://ncbi.nlm.nih.gov/pubmed/29273483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2017.12.001
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