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Responsiveness to basement membrane extract as a possible trait for tumorigenicity characterization

Immortalized cell lines used to produce vaccines are expected to be described in terms of their tumorigenicity. However, current in vivo tumorigenicity assays can be time-consuming and results can be equivocal, especially for weakly tumorigenic cells. Basement membrane extract (BME) derived from the...

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Detalhes bibliográficos
Publicado no:Vaccine X
Main Authors: Murata, Haruhiko, Omeir, Romelda, Tu, Wei, Lanning, Lynda, Phy, Kathryn, Foseh, Gideon, Lewis, Andrew M., Peden, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668224/
https://ncbi.nlm.nih.gov/pubmed/31384726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvacx.2019.100004
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