A Mouse Strain Defective in Both T Cells and NK Cells Has Enhanced Sensitivity to Tumor Induction by Plasmid DNA Expressing Both Activated H-Ras and c-Myc

As part of safety studies to evaluate the risk of residual cellular DNA in vaccines manufactured in tumorigenic cells, we have been developing in vivo assays to detect and quantify the oncogenic activity of DNA. We generated a plasmid expressing both an activated human H-ras gene and murine c-myc ge...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Sheng-Fowler, Li, Tu, Wei, Fu, Haiqing, Murata, Haruhiko, Lanning, Lynda, Foseh, Gideon, Macauley, Juliete, Blair, Donald, Hughes, Stephen H., Coffin, John M., Lewis, Andrew M., Peden, Keith
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193875/
https://ncbi.nlm.nih.gov/pubmed/25302710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108926
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