Failure-to-Thrive Syndrome Associated with Tumor Formation by Madin–Darby Canine Kidney Cells in Newborn Nude Mice

Tumors that formed in newborn nude mice that were inoculated with 10(7) Madin–Darby canine kidney (MDCK) cells were associated with a failure-to-thrive (FTT) syndrome consisting of growth retardation, lethargy, weakness, and dehydration. Scoliosis developed in 41% of affected pups. Pups were symptom...

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Autores principales: Brinster, Lauren R, Omeir, Romelda L, Foseh, Gideon S, Macauley, Juliete N, Snoy, Philip J, Beren, Joel J, Teferedegne, Belete, Peden, Keith, Lewis, Andrew M
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for Laboratory Animal Science 2013
Materias:
Mouse Models
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750667/
https://ncbi.nlm.nih.gov/pubmed/24209967
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