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A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity

The molecular mechanisms underlying spontaneous neoplastic transformation in cultured mammalian cells remain poorly understood, confounding recognition of parallels with the biology of naturally occurring cancer. The broad use of tumorigenic canine cell lines as research tools, coupled with the accu...

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Detalhes bibliográficos
Publicado no:Chromosome Res
Main Authors: Omeir, R., Thomas, R., Teferedegne, B., Williams, C., Foseh, G., Macauley, J., Brinster, L., Beren, J., Peden, K., Breen, M., Lewis, A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666904/
https://ncbi.nlm.nih.gov/pubmed/25957863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10577-015-9474-8
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