PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes

BACKGROUND: Phospholipase Cγ1 (PLCγ1) is highly expressed in human tumours. Our previous studies reported that both stable and inducible PLCγ1 down-regulation can inhibit formation of breast-cancer-derived experimental lung metastasis. Further, high expression of PLCγ1 and its constitutively activat...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Lattanzio, Rossano, Iezzi, Manuela, Sala, Gianluca, Tinari, Nicola, Falasca, Marco, Alberti, Saverio, Buglioni, Simonetta, Mottolese, Marcella, Perracchio, Letizia, Natali, Pier Giorgio, Piantelli, Mauro
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668079/
https://ncbi.nlm.nih.gov/pubmed/31362705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5949-x
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