Vav1 downmodulates Akt in different breast cancer subtypes: a new promising chance to improve breast cancer outcome

Targeting different members of the Akt pathways is a promising therapeutic chance in solid tumors including breast cancer. The variable expression levels of Akt isoforms with opposite effects on tumor growth and metastasis, however, make it difficult to select the inhibitors to be used for specific...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Oncol
Prif Awduron: Grassilli, Silvia, Brugnoli, Federica, Lattanzio, Rossano, Marchisio, Marco, Perracchio, Letizia, Piantelli, Mauro, Bavelloni, Alberto, Capitani, Silvano, Bertagnolo, Valeria
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026867/
https://ncbi.nlm.nih.gov/pubmed/29658179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12203
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