Vav1 downmodulates Akt in different breast cancer subtypes: a new promising chance to improve breast cancer outcome

Targeting different members of the Akt pathways is a promising therapeutic chance in solid tumors including breast cancer. The variable expression levels of Akt isoforms with opposite effects on tumor growth and metastasis, however, make it difficult to select the inhibitors to be used for specific...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Grassilli, Silvia, Brugnoli, Federica, Lattanzio, Rossano, Marchisio, Marco, Perracchio, Letizia, Piantelli, Mauro, Bavelloni, Alberto, Capitani, Silvano, Bertagnolo, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026867/
https://ncbi.nlm.nih.gov/pubmed/29658179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12203
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