Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer

Frizzled receptors mediate Wnt ligand signalling, which is crucially involved in regulating tissue development and differentiation, and is often deregulated in cancer. In this study, we found that the gene encoding the Wnt receptor frizzled 6 (FZD6) is frequently amplified in breast cancer, with an...

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Dettagli Bibliografici
Pubblicato in:J Pathol
Autori principali: Corda, Gabriele, Sala, Gianluca, Lattanzio, Rossano, Iezzi, Manuela, Sallese, Michele, Fragassi, Giorgia, Lamolinara, Alessia, Mirza, Hasan, Barcaroli, Daniela, Ermler, Sibylle, Silva, Elisabete, Yasaei, Hemad, Newbold, Robert F, Vagnarelli, Paola, Mottolese, Marcella, Natali, Pier Giorgio, Perracchio, Letizia, Quist, Jelmar, Grigoriadis, Anita, Marra, Pierfrancesco, Tutt, Andrew N, Piantelli, Mauro, Iacobelli, Stefano, De Laurenzi, Vincenzo, Sala, Arturo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2016
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Original Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248601/
https://ncbi.nlm.nih.gov/pubmed/27859262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4841
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