Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer

Frizzled receptors mediate Wnt ligand signalling, which is crucially involved in regulating tissue development and differentiation, and is often deregulated in cancer. In this study, we found that the gene encoding the Wnt receptor frizzled 6 (FZD6) is frequently amplified in breast cancer, with an...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Corda, Gabriele, Sala, Gianluca, Lattanzio, Rossano, Iezzi, Manuela, Sallese, Michele, Fragassi, Giorgia, Lamolinara, Alessia, Mirza, Hasan, Barcaroli, Daniela, Ermler, Sibylle, Silva, Elisabete, Yasaei, Hemad, Newbold, Robert F, Vagnarelli, Paola, Mottolese, Marcella, Natali, Pier Giorgio, Perracchio, Letizia, Quist, Jelmar, Grigoriadis, Anita, Marra, Pierfrancesco, Tutt, Andrew N, Piantelli, Mauro, Iacobelli, Stefano, De Laurenzi, Vincenzo, Sala, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2016
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248601/
https://ncbi.nlm.nih.gov/pubmed/27859262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4841
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