Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma

The endosialin/CD248/TEM1 receptor is expressed on the cell surface of tumor-associated stroma cells as well as in sarcoma and neuroblastoma cells. This receptor is emerging as an attractive molecule in diagnostics and therapeutics because of its expression across the stroma of many human tumors, th...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Capone, Emily, Piccolo, Enza, Fichera, Imma, Ciufici, Paolo, Barcaroli, Daniela, Sala, Arturo, De Laurenzi, Vincenzo, Iacobelli, Valentina, Iacobelli, Stefano, Sala, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601145/
https://ncbi.nlm.nih.gov/pubmed/28947977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19499
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