Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma

The endosialin/CD248/TEM1 receptor is expressed on the cell surface of tumor-associated stroma cells as well as in sarcoma and neuroblastoma cells. This receptor is emerging as an attractive molecule in diagnostics and therapeutics because of its expression across the stroma of many human tumors, th...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Capone, Emily, Piccolo, Enza, Fichera, Imma, Ciufici, Paolo, Barcaroli, Daniela, Sala, Arturo, De Laurenzi, Vincenzo, Iacobelli, Valentina, Iacobelli, Stefano, Sala, Gianluca
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601145/
https://ncbi.nlm.nih.gov/pubmed/28947977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19499
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