Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma

SIMPLE SUMMARY: Antibody Drug Conjugates are an emerging class of biopharmaceuticals that have seen an impressive increase of attention in the field of cancer therapy. Here, we describe the therapeutic activity of 1959-sss/DM3, a non-internalizing ADC targeting LGALS3BP, a secreted, extracellular ve...

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Publicado no:Cancers (Basel)
Main Authors: Capone, Emily, Lamolinara, Alessia, Pastorino, Fabio, Gentile, Roberta, Ponziani, Sara, Di Vittorio, Giulia, D’Agostino, Daniela, Bibbò, Sandra, Rossi, Cosmo, Piccolo, Enza, Iacobelli, Valentina, Lattanzio, Rossano, Panella, Valeria, Sallese, Michele, De Laurenzi, Vincenzo, Giansanti, Francesco, Sala, Arturo, Iezzi, Manuela, Ponzoni, Mirco, Ippoliti, Rodolfo, Iacobelli, Stefano, Sala, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650653/
https://ncbi.nlm.nih.gov/pubmed/33076448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102989
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