Repurposing a psychoactive drug for children with cancer: p27(Kip1)-dependent inhibition of metastatic neuroblastomas by Prozac

The MYC family of transcription factors is a major driver of human cancer and potential therapeutic target. However, no clinically viable drugs have been yet developed that are able to directly tackle MYC oncoproteins. In our laboratory, we are exploring alternative approaches aiming to disturb sign...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Bibbo’, Sandra, Lamolinara, Alessia, Capone, Emily, Purgato, Stefania, Tsakaneli, Alexia, Panella, Valeria, Sallese, Michele, Rossi, Cosmo, Ciufici, Paolo, Nieddu, Valentina, De Laurenzi, Vincenzo, Iezzi, Manuela, Perini, Giovanni, Sala, Gianluca, Sala, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949307/
https://ncbi.nlm.nih.gov/pubmed/31900399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-019-0186-3
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