Repurposing a psychoactive drug for children with cancer: p27(Kip1)-dependent inhibition of metastatic neuroblastomas by Prozac

The MYC family of transcription factors is a major driver of human cancer and potential therapeutic target. However, no clinically viable drugs have been yet developed that are able to directly tackle MYC oncoproteins. In our laboratory, we are exploring alternative approaches aiming to disturb sign...

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Detalles Bibliográficos
Publicado en:Oncogenesis
Autores principales: Bibbo’, Sandra, Lamolinara, Alessia, Capone, Emily, Purgato, Stefania, Tsakaneli, Alexia, Panella, Valeria, Sallese, Michele, Rossi, Cosmo, Ciufici, Paolo, Nieddu, Valentina, De Laurenzi, Vincenzo, Iezzi, Manuela, Perini, Giovanni, Sala, Gianluca, Sala, Arturo
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949307/
https://ncbi.nlm.nih.gov/pubmed/31900399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-019-0186-3
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