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Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras
The Ras family of small GTPases modulates numerous essential processes. Activating Ras mutations result in hyper-activation of selected signaling cascades, which leads to human diseases. The high frequency of Ras mutations in human malignant neoplasms has led to Ras being a desirable chemotherapeuti...
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| I publikationen: | Sci Rep |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group UK
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6667474/ https://ncbi.nlm.nih.gov/pubmed/31363101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46677-9 |
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