Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking

Apicomplexan parasites possess a plastid organelle called the apicoplast. Inhibitors that selectively target apicoplast housekeeping functions, including DNA replication and protein translation, are lethal for the parasite, and several (doxycycline, clindamycin, and azithromycin) are in clinical use...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:PLoS Biol
Autores principales: Kennedy, Kit, Cobbold, Simon A., Hanssen, Eric, Birnbaum, Jakob, Spillman, Natalie J., McHugh, Emma, Brown, Hannah, Tilley, Leann, Spielmann, Tobias, McConville, Malcolm J., Ralph, Stuart A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667170/
https://ncbi.nlm.nih.gov/pubmed/31318858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000376
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares