Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking

Apicomplexan parasites possess a plastid organelle called the apicoplast. Inhibitors that selectively target apicoplast housekeeping functions, including DNA replication and protein translation, are lethal for the parasite, and several (doxycycline, clindamycin, and azithromycin) are in clinical use...

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Detaylı Bibliyografya
Yayımlandı:PLoS Biol
Asıl Yazarlar: Kennedy, Kit, Cobbold, Simon A., Hanssen, Eric, Birnbaum, Jakob, Spillman, Natalie J., McHugh, Emma, Brown, Hannah, Tilley, Leann, Spielmann, Tobias, McConville, Malcolm J., Ralph, Stuart A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667170/
https://ncbi.nlm.nih.gov/pubmed/31318858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000376
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