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p53-Dependent Transcriptional Control of Cellular Prion by Presenilins
The presenilin-dependent γ-secretase processing of the β-amyloid precursor protein (βAPP) conditions the length of the amyloid β peptides (Aβ) that accumulate in the senile plaques of Alzheimer's disease-affected brains. This, together with an additional presenilin-mediated ε-secretase cleavage...
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| Pubblicato in: | J Neurosci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6665908/ https://ncbi.nlm.nih.gov/pubmed/19458243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0789-09.2009 |
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