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p53-Dependent Transcriptional Control of Cellular Prion by Presenilins

The presenilin-dependent γ-secretase processing of the β-amyloid precursor protein (βAPP) conditions the length of the amyloid β peptides (Aβ) that accumulate in the senile plaques of Alzheimer's disease-affected brains. This, together with an additional presenilin-mediated ε-secretase cleavage...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Vincent, Bruno, Sunyach, Claire, Orzechowski, Hans-Dieter, St George-Hyslop, Peter, Checler, Frédéric
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665908/
https://ncbi.nlm.nih.gov/pubmed/19458243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0789-09.2009
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