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Conformational selection dominates binding of steroids to human cytochrome P450 17A1
Cytochrome P450 (P450, CYP) enzymes are the major catalysts involved in the oxidation of steroids as well as many other compounds. Their versatility has been explained in part by flexibility of the proteins and complexity of the binding mechanisms. However, whether these proteins bind their substrat...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6664176/ https://ncbi.nlm.nih.gov/pubmed/31072872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008860 |
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