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DNA duplex recognition activates Exo1 nuclease activity

Exonuclease 1 (Exo1) is an evolutionarily conserved eukaryotic nuclease that plays a multifaceted role in maintaining genome stability. The biochemical attributes of Exo1 have been extensively characterized via conventional assays. However, the key step governing its activation remains elusive. Exte...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Li, Yuxi, Shen, Jiangchuan, Niu, Hengyao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663874/
https://ncbi.nlm.nih.gov/pubmed/31182486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008549
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