14-3-3 Proteins Restrain the Exo1 Nuclease to Prevent Overresection

The DNA end resection process dictates the cellular response to DNA double strand break damage and is essential for genome maintenance. Although insufficient DNA resection hinders homology-directed repair and ATR (ataxia telangiectasia and Rad3 related)-dependent checkpoint activation, overresection...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Chen, Xiaoqing, Kim, In-Kwon, Honaker, Yuchi, Paudyal, Sharad C., Koh, Won Kyun, Sparks, Melanie, Li, Shan, Piwnica-Worms, Helen, Ellenberger, Tom, You, Zhongsheng
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
DNA and Chromosomes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424361/
https://ncbi.nlm.nih.gov/pubmed/25833945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.644005
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky