Cardiolipin-induced activation of pyruvate dehydrogenase links mitochondrial lipid biosynthesis to TCA cycle function

Cardiolipin (CL) is the signature phospholipid of mitochondrial membranes. Although it has long been known that CL plays an important role in mitochondrial bioenergetics, recent evidence in the yeast model indicates that CL is also essential for intermediary metabolism. To gain insight into the func...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Li, Yiran, Lou, Wenjia, Raja, Vaishnavi, Denis, Simone, Yu, Wenxi, Schmidtke, Michael W., Reynolds, Christian A., Schlame, Michael, Houtkooper, Riekelt H., Greenberg, Miriam L.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663869/
https://ncbi.nlm.nih.gov/pubmed/31186346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009037
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