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Loss of tafazzin results in decreased myoblast differentiation in C2C12 cells: A myoblast model of Barth syndrome and cardiolipin deficiency

Barth syndrome (BTHS) is an X-linked genetic disorder resulting from mutations in the tafazzin gene (TAZ), which encodes the transacylase that remodels the mitochondrial phospholipid cardiolipin (CL). While most BTHS patients exhibit pronounced skeletal myopathy, the mechanisms linking defective CL...

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Bibliografische gegevens
Gepubliceerd in:Biochim Biophys Acta
Hoofdauteurs: Lou, Wenjia, Reynolds, Christian A., Li, Yiran, Liu, Jenney, Hüttemann, Maik, Schlame, Michael, Stevenson, David, Strathdee, Douglas, Greenberg, Miriam L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976547/
https://ncbi.nlm.nih.gov/pubmed/29694924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2018.04.015
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