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Loss of tafazzin results in decreased myoblast differentiation in C2C12 cells: A myoblast model of Barth syndrome and cardiolipin deficiency

Barth syndrome (BTHS) is an X-linked genetic disorder resulting from mutations in the tafazzin gene (TAZ), which encodes the transacylase that remodels the mitochondrial phospholipid cardiolipin (CL). While most BTHS patients exhibit pronounced skeletal myopathy, the mechanisms linking defective CL...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Lou, Wenjia, Reynolds, Christian A., Li, Yiran, Liu, Jenney, Hüttemann, Maik, Schlame, Michael, Stevenson, David, Strathdee, Douglas, Greenberg, Miriam L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976547/
https://ncbi.nlm.nih.gov/pubmed/29694924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2018.04.015
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