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Cardiolipin-induced activation of pyruvate dehydrogenase links mitochondrial lipid biosynthesis to TCA cycle function

Cardiolipin (CL) is the signature phospholipid of mitochondrial membranes. Although it has long been known that CL plays an important role in mitochondrial bioenergetics, recent evidence in the yeast model indicates that CL is also essential for intermediary metabolism. To gain insight into the func...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Li, Yiran, Lou, Wenjia, Raja, Vaishnavi, Denis, Simone, Yu, Wenxi, Schmidtke, Michael W., Reynolds, Christian A., Schlame, Michael, Houtkooper, Riekelt H., Greenberg, Miriam L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663869/
https://ncbi.nlm.nih.gov/pubmed/31186346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009037
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