Heterozygous mutations in valosin-containing protein (VCP) and resistance to VCP inhibitors

In recent years, multiple studies including ours have reported on the mechanism of resistance towards valosin-containing protein (VCP) inhibitors. While all these studies reported target alterations via mutations in VCP as the primary mechanism of resistance, discrepancies persist to date regarding...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Bastola, Prabhakar, Bilkis, Rabeya, De Souza, Cristabelle, Minn, Kay, Chien, Jeremy
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662852/
https://ncbi.nlm.nih.gov/pubmed/31358864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47085-9
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