Modifying PTEN recruitment promotes neuron survival, regeneration, and functional recovery after CNS injury

Phosphatase and tensin homolog (PTEN) regulates apoptosis and axonal growth in the developing and adult central nervous system (CNS). Here, we show that human PTEN C-terminal PDZ interactions play a critical role in neuronal apoptosis and axon regeneration after traumatic CNS injury and stroke, high...

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Vydáno v:Cell Death Dis
Hlavní autoři: Shabanzadeh, Alireza Pirsaraei, D’Onofrio, Philippe Matteo, Magharious, Mark, Choi, Kyung An Brian, Monnier, Philippe Patrick, Koeberle, Paulo Dieter
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662832/
https://ncbi.nlm.nih.gov/pubmed/31358730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1802-z
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