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Probing conformational changes of monomeric transthyretin with second derivative fluorescence

We have studied the intrinsic fluorescence spectra of a monomeric variant of human transthyretin (M-TTR), a protein involved in the transport of the thyroid hormone and retinol and associated with various forms of amyloidosis, extending our analysis to the second order derivative of the spectra. Thi...

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Vydáno v:Sci Rep
Hlavní autoři: Jazaj, Denisa, Ghadami, Seyyed Abolghasem, Bemporad, Francesco, Chiti, Fabrizio
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662758/
https://ncbi.nlm.nih.gov/pubmed/31358790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47230-4
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