Tryptophan fluorescence yields and lifetimes as a probe of conformational changes in human glucokinase

Five variants of glucokinase (ATP-D-hexose-6-phosphotransferase, EC 2.7.1.1) including wild type and single Trp mutants with the Trp residue at positions 65, 99, 167 and 257 were prepared. The fluorescence of Trp in all locations studied showed intensity changes when glucose bound, indicating that c...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Fluoresc
Auteurs principaux: Zelent, Bogumil, Bialas, Chris, Gryczynski, Ignacy, Chen, Pan, Chib, Rahul, Lewerissa, Karina, Corradini, Maria G., Ludescher, Richard D., Vanderkooi, Jane M., Matschinsky, Franz M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025808/
https://ncbi.nlm.nih.gov/pubmed/28432632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10895-017-2099-x
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires