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Quantitative Systems Pharmacology Model of Chimeric Antigen Receptor T‐Cell Therapy

Chimeric antigen receptor T‐cell (CART) therapy is a new and promising cancer therapy. However, severe toxicity due to cytokine release syndrome (CRS) in CART‐treated patients highlighted the possible danger of this new therapy. Disease burden and CART doses are the potential factors associated with...

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Publicado en:Clin Transl Sci
Autores principales: Hardiansyah, Deni, Ng, Chee Meng
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662387/
https://ncbi.nlm.nih.gov/pubmed/30990958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12636
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