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Development of molecular and pharmacological switches for chimeric antigen receptor T cells

The use of chimeric antigen receptor (CAR) T cell technology as a therapeutic strategy for the treatment blood-born human cancers has delivered outstanding clinical efficacy. However, this treatment modality can also be associated with serious adverse events in the form of cytokine release syndrome....

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Podrobná bibliografie
Vydáno v:Exp Hematol Oncol
Hlavní autoři: Wu, Bill X., Song, No-Joon, Riesenberg, Brian P., Li, Zihai
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833279/
https://ncbi.nlm.nih.gov/pubmed/31709128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-019-0151-z
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