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Quantitative Systems Pharmacology Model of Chimeric Antigen Receptor T‐Cell Therapy

Chimeric antigen receptor T‐cell (CART) therapy is a new and promising cancer therapy. However, severe toxicity due to cytokine release syndrome (CRS) in CART‐treated patients highlighted the possible danger of this new therapy. Disease burden and CART doses are the potential factors associated with...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Hardiansyah, Deni, Ng, Chee Meng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662387/
https://ncbi.nlm.nih.gov/pubmed/30990958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12636
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