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DNMT3a-triggered downregulation of K(2p)1.1 gene in primary sensory neurons contributes to paclitaxel-induced neuropathic pain
Antineoplastic drugs induce dramatic transcriptional changes in dorsal root ganglion (DRG) neurons, which may contribute to chemotherapy-induced neuropathic pain. K(2p)1.1 controls neuronal excitability by setting the resting membrane potential. Here, we report that systemic injection of the chemoth...
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| Publicado no: | Int J Cancer |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6660426/ https://ncbi.nlm.nih.gov/pubmed/30684388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.32155 |
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