טוען...

Global view of the RAF-MEK-ERK module and its immediate downstream effectors

Small molecule inhibitors of BRAF and MEK have proven effective at inhibiting tumor growth in melanoma patients, however this efficacy is limited due to the almost universal development of drug resistance. To provide advanced insight into the signaling responses that occur following kinase inhibitio...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Santini, Cristina C., Longden, James, Schoof, Erwin M., Simpson, Craig D., Jeschke, Grace R., Creixell, Pau, Kim, Jinho, Wu, Xuewei, Turk, Benjamin E., Rosen, Neal, Poulikakos, Poulikos I., Linding, Rune
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659682/
https://ncbi.nlm.nih.gov/pubmed/31350469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47245-x
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!