Global view of the RAF-MEK-ERK module and its immediate downstream effectors

Small molecule inhibitors of BRAF and MEK have proven effective at inhibiting tumor growth in melanoma patients, however this efficacy is limited due to the almost universal development of drug resistance. To provide advanced insight into the signaling responses that occur following kinase inhibitio...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Santini, Cristina C., Longden, James, Schoof, Erwin M., Simpson, Craig D., Jeschke, Grace R., Creixell, Pau, Kim, Jinho, Wu, Xuewei, Turk, Benjamin E., Rosen, Neal, Poulikakos, Poulikos I., Linding, Rune
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659682/
https://ncbi.nlm.nih.gov/pubmed/31350469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47245-x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker