Unexpected Activity of Oral Fosfomycin against Resistant Strains of Escherichia coli in Murine Pyelonephritis

Fosfomycin tromethamine activity is well established for oral treatment of uncomplicated lower urinary tract infections, but little is known about its potential efficacy in pyelonephritis. Ascending pyelonephritis was induced in mice infected with 6 strains of Escherichia coli (fosfomycin MICs, 1 μg...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Pourbaix, Annabelle, Guérin, François, Burdet, Charles, Massias, Laurent, Chau, Françoise, Cattoir, Vincent, Fantin, Bruno
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658801/
https://ncbi.nlm.nih.gov/pubmed/31160291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00903-19
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