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Ciprofloxacin Treatment Failure in a Murine Model of Pyelonephritis Due to an AAC(6′)-Ib-cr-Producing Escherichia coli Strain Susceptible to Ciprofloxacin In Vitro

AAC(6′)-Ib-cr is a plasmid-mediated quinolone resistance mechanism described worldwide for Escherichia coli. Since it confers in vitro only a low level of resistance to ciprofloxacin, we evaluated its impact on the in vivo activity of ciprofloxacin. Isogenic strains were obtained by transferring pla...

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Detalles Bibliográficos
Main Authors: Guillard, T., Cambau, E., Chau, F., Massias, L., de Champs, C., Fantin, B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837926/
https://ncbi.nlm.nih.gov/pubmed/24018262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01489-13
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