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Towards a structural view of drug binding to hERG K(+) channels:
The human ether-a-go-go-related gene (HERG) K(+) channel is of great medical and pharmaceutical relevance. Inherited mutations in hERG result in congenital long QT syndrome, which is associated with a marked increased risk of cardiac arrhythmias and sudden death. hERG K(+) channels are also remarkab...
Sparad:
| I publikationen: | Trends Pharmacol Sci |
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| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6658208/ https://ncbi.nlm.nih.gov/pubmed/28711156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2017.06.004 |
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