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Hydroalkynylative cyclization of 1,6-enynes with terminal alkynes

A rhodium-catalyzed highly regio- and enantioselective hydroalkynylation, generating cis-hydrobenzofuranone-tethered enynes has been developed. The reaction proceeds with a selective head-to-head insertion and symmetry breaking Michael addition cascade. One product was produced from tens of possible...

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Bibliografische gegevens
Gepubliceerd in:Chem Sci
Hoofdauteurs: Teng, Qi, Thirupathi, Nuligonda, Tung, Chen-Ho, Xu, Zhenghu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Royal Society of Chemistry 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657412/
https://ncbi.nlm.nih.gov/pubmed/31391909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc02341k
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