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Lumiflavin increases the sensitivity of ovarian cancer stem‐like cells to cisplatin by interfering with riboflavin

Here, we used lumiflavin, an inhibitor of riboflavin, as a new potential therapeutic chemosensitizer to ovarian cancer stem‐like cells (CSCs). This study demonstrates that the enrichment of riboflavin in CSCs is an important cause of its resistance to chemotherapy. Lumiflavin can effectively reduce...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Yang, Ruhui, Wei, Zhe, Wu, Songquan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652702/
https://ncbi.nlm.nih.gov/pubmed/31187586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14409
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