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Lumiflavin increases the sensitivity of ovarian cancer stem‐like cells to cisplatin by interfering with riboflavin

Here, we used lumiflavin, an inhibitor of riboflavin, as a new potential therapeutic chemosensitizer to ovarian cancer stem‐like cells (CSCs). This study demonstrates that the enrichment of riboflavin in CSCs is an important cause of its resistance to chemotherapy. Lumiflavin can effectively reduce...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Yang, Ruhui, Wei, Zhe, Wu, Songquan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652702/
https://ncbi.nlm.nih.gov/pubmed/31187586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14409
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