Sensitizing ovarian cancer cells to chemotherapy by interfering with pathways that are involved in the formation of cancer stem cells

Chemotherapy often fails to eradicate cancer stem cells (CSCs) that drive cancer recurrence. In fact, the treated tumors often contain a higher frequency of chemo-resistant CSCs. It is thought that CSC formation is supported by exposure of cancer cells to sub-cytotoxic chemotherapy doses as a result...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Saydaminova, Kamola, Strauss, Robert, Xie, Min, Bartek, Jiri, Richter, Maximilian, van Rensburg, Ruan, Drescher, Charles, Ehrhardt, Anja, Ding, Sheng, Lieber, André
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079387/
https://ncbi.nlm.nih.gov/pubmed/27574825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1219819
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