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Lumiflavin increases the sensitivity of ovarian cancer stem‐like cells to cisplatin by interfering with riboflavin

Here, we used lumiflavin, an inhibitor of riboflavin, as a new potential therapeutic chemosensitizer to ovarian cancer stem‐like cells (CSCs). This study demonstrates that the enrichment of riboflavin in CSCs is an important cause of its resistance to chemotherapy. Lumiflavin can effectively reduce...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Main Authors: Yang, Ruhui, Wei, Zhe, Wu, Songquan
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652702/
https://ncbi.nlm.nih.gov/pubmed/31187586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14409
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