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Genetic Defects in Mitochondrial Dynamics in Caenorhabditis elegans Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration

Background: Parkinson’s disease (PD) is one of the most common neurodegenerative disorders involving devastating loss of dopaminergic neurons in the substantia nigra. Early steps in PD pathogenesis include mitochondrial dysfunction, and mutations in mitochondrial genes have been linked to familial f...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hartman, Jessica H., Gonzalez-Hunt, Claudia, Hall, Samantha M., Ryde, Ian T., Caldwell, Kim A., Caldwell, Guy A., Meyer, Joel N.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651461/
https://ncbi.nlm.nih.gov/pubmed/31261893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20133202
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