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Genetic Defects in Mitochondrial Dynamics in Caenorhabditis elegans Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration

Background: Parkinson’s disease (PD) is one of the most common neurodegenerative disorders involving devastating loss of dopaminergic neurons in the substantia nigra. Early steps in PD pathogenesis include mitochondrial dysfunction, and mutations in mitochondrial genes have been linked to familial f...

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Foilsithe in:Int J Mol Sci
Main Authors: Hartman, Jessica H., Gonzalez-Hunt, Claudia, Hall, Samantha M., Ryde, Ian T., Caldwell, Kim A., Caldwell, Guy A., Meyer, Joel N.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651461/
https://ncbi.nlm.nih.gov/pubmed/31261893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20133202
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