Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis elegans

Neurodegeneration has been correlated with mitochondrial DNA (mtDNA) damage and exposure to environmental toxins, but causation is unclear. We investigated the ability of several known environmental genotoxins and neurotoxins to cause mtDNA damage, mtDNA depletion, and neurodegeneration in Caenorhab...

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Pubblicato in:PLoS One
Autori principali: González-Hunt, Claudia P., Leung, Maxwell C. K., Bodhicharla, Rakesh K., McKeever, Madeline G., Arrant, Andrew E., Margillo, Kathleen M., Ryde, Ian T., Cyr, Derek D., Kosmaczewski, Sara G., Hammarlund, Marc, Meyer, Joel N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259338/
https://ncbi.nlm.nih.gov/pubmed/25486066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114459
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